What is Hair Mesotherapy?
Hair mesotherapy is a non-invasive treatment method that aims to revitalize hair follicles and support hair health, based on the application of micro-injections of nutrients such as vitamins, minerals, amino acids and peptides to the scalp using thin needles or a mesotherapy gun.
How is Hair Mesotherapy Applied?
Before the hair mesotherapy session, the scalp is cleaned and numbed with a local anesthetic cream; then, a special cocktail is applied in equal doses to hundreds of micro channels opened at a depth of approximately 1–2 millimeters, using very fine-tipped mesotherapy needles or an automatic microinjection device; sessions are planned at weekly or biweekly intervals, for a total of 4–8 sessions.
Mesotherapy before and after FUE hair transplantation
Mesotherapy before FUE hair transplantation is effective in protecting the existing hair, thickening the hair strands, having bright and shiny hair and preventing hair loss problems.
After sapphire hair transplantation, mesotherapy accelerates angiogenesis (new vessel formation) and supplies the transplanted hair grafts with growth factors, stimulating them. It is an advantageous method to help recover hair in a faster way, after the shock loss. Thanks to the mineral and amino acids it contains, it positively affects the hair’s thickness and texture.
How is mesotherapy applied?
Mesotherapy is applied by making injections to the affected areas. Local anaesthesia is used to the site of application before the injections. Your doctor determines the amount mixture for each injection, and only after that, mesotherapy injected under the skin.
Will I feel pain during the mesotherapy procedure?
Before the procedure, the patient is provided maximum comfort by applying a pain reliever and anaesthetic cream to the skin. However, the patient may feel a small amount of pain and pain according to his/her pain threshold. The needle tips used for mesotherapy are concise and thin.
What is the Benefit of Hair Mesotherapy?
This method accelerates cell renewal by increasing blood circulation in the hair follicles, ensures stronger hair growth, slows down existing thinning and helps prevent thinning of hair strands; it also optimizes scalp health by regulating the oil and dandruff balance on the scalp.
THE EFFECT AND BENEFITS OF MESOTHERAPY ON HAIR
- It is instrumental in protecting existing hair.
- Mesotherapy is much more useful than topical hair care methods.
- Successful results are obtained when applied against the problem of dandruff.
- It helps preserve hair colour and prevent/delaying bleaching.
- Gives shine, vitality and volume to hair.
- Extends the life of the hair.
- It is useful in thickening and strengthening the hair strands.
What are the side effects of mesotherapy?
Mesotherapy has no severe side effects. Very rarely, itching due to oedema and allergic reactions can be seen.
How many times should a person have mesotherapy after sapphire hair transplantation?
Our clinic sees it beneficial to perform hair mesotherapy for 8-12 months in the number of sessions deemed appropriate by the physician, starting from the 1st month after the sapphire hair transplantation procedure and one month apart, depending on the medications used in the procedure. Also, the frequency of application differs from person to person. When applied in the right clinic by experienced and professional physicians, successful results are obtained from the treatment.
What is Included in Hair Mesotherapy?
Mesotherapy cocktails generally include B complex vitamins that support energy production and cell renewal, and biotin that strengthens the subcutaneous tissue; various amino acids that serve as the basic building blocks of hair structure; minerals such as zinc and magnesium that play a critical role in cell metabolism; coenzymes that increase antioxidant defense; and peptides that stimulate the cells around the follicle and encourage hair growth, all working together to nourish and vitalize the hair follicles.
Vitamins (B Complex, Biotin etc.)
B complex vitamins; micronutrients such as B1, B2, B3, B5, B6, B12 and biotin increase cellular energy production in hair roots and ensure that follicles in the growth phase remain more vibrant. Biotin, in particular, improves keratin synthesis and increases hair strand durability and elasticity. In addition, thanks to niacin (B3), microcirculation in the scalp is accelerated; thus, hair roots are more effectively fed with oxygen and other nutrients.
Amino Acids
The hair strand is essentially a protein structure called keratin, and the basic building blocks of keratin are amino acids. When selected amino acids such as L-lesine, L-cysteine, L-glutamine are added to the mesotherapy cocktail, new protein synthesis in the hair follicles is encouraged. In this way, thin and fragile hair strands become thicker, the risk of breakage is reduced, and the natural growth cycle of the hair is supported.
Minerals
Minerals such as zinc, iron, magnesium and manganese play critical roles in hair health. Zinc strengthens the structure of keratin fibers and prevents hair loss by reducing inflammation; iron improves the energy metabolism of the follicles by increasing oxygen transport. Magnesium and manganese activate cellular repair mechanisms and maintain the integrity of the scalp tissue.
Coenzymes
Coenzymes are organic molecules that accelerate biochemical reactions within the cell. When coenzyme supplements such as NADH and CoQ10 are used in mesotherapy, mitochondrial energy production in hair follicles is strengthened. Thus, follicles work more efficiently, cell renewal is accelerated and the molecular infrastructure necessary for hair growth is strengthened.
Peptides That Promote Hair Growth
Peptides are short-chain amino acid sequences that play a decisive role in cell signaling. Keratin growth factor (KGF) peptides in particular stimulate the dermal papilla cells in the hair follicles, shortening the time it takes to enter the active growth phase. In addition, innovative formulas such as CPD-Winning Peptide™ support the hair follicles in transitioning from the resting phase to the growth phase, providing a more intense and rapid increase in density.
Male Pattern Hair Loss
Male pattern hair loss is a condition characterized by the receding hairline and thinning of the crown, which occurs as a result of genetic and hormonal factors coming together. The DHT hormone, which increases in androgen-sensitive follicular units, causes the follicles to shrink and enter a resting phase, eventually regressing completely. Hair mesotherapy comes into play during this process, speeds up microcirculation that nourishes the hair roots, and provides follicles with resistance with vitamin and mineral cocktails. Regular sessions provide additional support against genetic predisposition, slowing down the rate of shedding and strengthening existing hair.
Female Pattern Hair Thinning
Diffuse hair thinning, which is frequently seen in women, can be caused by factors such as hormonal fluctuations, post-pregnancy changes or thyroid dysfunction. This type of shedding manifests itself as a homogeneous thinning of the entire scalp; the front line is usually preserved while the crown area is slightly opened. The amino acid and peptide mixtures applied with mesotherapy support keratin synthesis, which plays a critical role in hair strand formation. At the same time, B complex vitamins and biotin regulate scalp metabolism, stimulate new hair formation and help thicken existing strands.
Stress-Related Hair Loss
Intense living conditions, work stress or psychological traumas disrupt the body’s hormonal balance; increased cortisol levels negatively affect the hair follicle cycle. In this case, hair follicles first enter the resting phase more often, then mass shedding may be observed. Hair mesotherapy helps follicles return to the active growth phase with coenzyme supports that eliminate stress-related microcirculation disorders and accelerate cellular repair mechanisms. Regular applications shorten the shedding phase by improving the nutrition of stressed follicles.
Seasonal Hair Loss
During seasonal transitions, hair loss, which increases slightly especially towards autumn, is a normal physiological reaction. In order to control this cyclical loss, mesotherapy provides rich nutritional supplements to the skin with the minerals and vitamins in its cocktail. Minerals such as zinc and iron strengthen the follicles weakened by seasonal fatigue; coenzymes and peptides support cell renewal, reducing the severity of shedding and minimizing seasonal thinning.
Support for Intensive Hair Treatments
Hair mesotherapy is the ideal complement to other intensive hair loss treatments such as minoxidil, PRP or laser. Injected amino acid and peptide mixtures synergize with PRP applications, increasing the effectiveness of growth factors. It also relieves irritation caused by topical or systemic treatments and increases the bioavailability of the follicles. This combined approach provides faster results, even in difficult cases, and maintains hair health at a high level in the long term.
WHO IS ELIGIBLE FOR MESOTHERAPY?
Mesotherapy can be applied for the patients with hair loss problems, a genetic predisposition to hair loss, or sudden hair loss due to a diet. Successful results are obtained from the therapy. Besides, mesotherapy is effective in people who complain of weak and worn hair, and in cases such as late hair growth. Mesotherapy is eligible for the people of all ages.
WHO IS NOT ELIGIBLE FOR MESOTHERAPY?
Mesotherapy is not advised for patients with cancer, diabetes, who use anticoagulants and breastfeeding women. Patients who want to have mesotherapy treatment should inform their doctor about the medications they use and the diseases they have or have been through.
How Long Does It Take for Hair Mesotherapy to Show Effects?
The effectiveness of hair mesotherapy usually begins to be observed within 4 to 6 weeks following the application. After the first session, blood circulation in the scalp improves and new fine hair begins to grow. By the end of the 3rd month, a noticeable thickening of the hair strands and an increase in breakage resistance are felt. From the sixth month onwards, the effects of the vitamins, amino acids and peptides in the mesotherapy cocktail are fully established; a permanent increase in hair density and shine is achieved.
How Many Sessions Does the Application Take?
Standard protocols form the basis of the first four applications planned with one session interval. Following this intensive initial period, reinforcement sessions are held once a month to complete the total number of sessions to 6–8. In some patients, depending on the cyclical shedding pattern or the need for additional treatment, protective touch sessions may be recommended 2–3 times a year. Each session lasts approximately 30–45 minutes and does not require a break from social life.
Things to Consider After Hair Mesotherapy
After mesotherapy, water contact with the scalp should be limited for the first 24 hours, and excessively hot showers and saunas should be avoided. If there is crusting or redness, prescribed soothing lotions should be used, and a hat or high factor sunscreen should be preferred to protect from the sun’s rays. The scalp should not be massaged for the first week, and chemical care products should be postponed.
MESOTHERAPY IN SMILE HAIR CLINIC
In Smile Hair Clinic, mesotherapy is applied by physicians who have completed the necessary certifications and are known worldwide. The previous medical history of the patients thoroughly evaluated.
The patient is informed in details about all stages and can always reach his physician and easily ask them all the questions. The procedure is carried out in a hygienic environment with comfort. After the process, you are discharged with your doctor’s recommendations.
Frequently asked Questions
Is Hair Mesotherapy Permanent?
Mesotherapy alone does not provide a permanent surgical solution; however, with regular applications, the health cycle of the follicles is supported and the rate of shedding is slowed down in the long term. Although the effects gradually decrease when the application is stopped, it is recommended to include it in a continuous maintenance program as the hair quality and skin vitality gained are preserved for six months to one year.
Is Hair Mesotherapy Risky? Are There Any Side Effects?
Since the procedure is performed with very fine needles, the pain is minimal and local anesthetic creams relieve the pain. The risk of infection or allergic reaction is extremely low; with hygienic application and quality product selection, the possibility of side effects drops below 1%. Very mild redness, edema or bruising may rarely occur and will resolve spontaneously within one to two days.
Does mesotherapy grow hair or just stop hair loss?
Hair mesotherapy is not a method that directly guarantees new hair growth, but aims to reduce the rate of hair loss by providing nutrition and revitalization to existing follicles. Vitamin, mineral, amino acid and peptide cocktails administered through microinjections repair the weakened metabolism of hair follicles and stimulate cell renewal. These improved environmental conditions facilitate the transition of follicles in the resting phase to the regrowth phase; therefore, both the rate of hair loss decreases and the emergence of new thin hair strands after shock loss is supported. However, mesotherapy alone is not sufficient in areas with permanent follicle loss; surgical reinforcement (planting) may be required in those areas.
What is the difference with PRP?
PRP (Platelet Rich Plasma) is based on the injection of platelets in the blood that are enriched with growth factors; these factors are effective in wound healing and tissue regeneration. Mesotherapy, on the other hand, carries pre-formulated nutrient cocktails directly to the target area. While PRP uses the body’s own plasma resources in a single session, mesotherapy offers the combined effect of a wide variety of components such as vitamins, minerals, amino acids, coenzymes and peptides. The biggest difference between them is that PRP is an autologous biological approach, while mesotherapy offers a formulated, multi-element nutritional treatment.
Can it be done after hair transplantation?
Yes, following hair transplantation, the attachment and growth processes of the transplanted follicles can be supported with mesotherapy applications. After the shock loss period of 4–6 weeks after transplantation, mesotherapy cocktails accelerate the reactivation of the follicles; when combined with PRP, a synergistic effect occurs. This additional support ensures that the transplantation results are faster and more intense, helping to achieve the final density in a shorter time than expected.
Is it a painful procedure?
The thin needles and mesotherapy gun used during mesotherapy offer a minimally invasive application. Local anesthetic creams applied to the scalp before the procedure greatly reduce needle pricks. Most patients report experiencing only a slight tingling or stinging sensation; pain thresholds are not high and the process is comfortable. The rare mild redness or edema seen after the procedure is quickly controlled with cold compresses and prescription soothing gels.
Can hair mesotherapy be applied at home?
Professional mesotherapy devices are a delicate application that requires dose control, needle angle and depth adjustment; therefore, there is no safe formulation and device that will provide the same effect at home. Although there are spray or ampoule formulas on the market that promise similar effects, they cannot penetrate the deep dermal layer sufficiently. Cocktails that require injection techniques should only be applied by experts and under sterile conditions. At home, bioactive shampoos or topical serums that will support the mesotherapy effect can be preferred; however, real mesotherapy should only be performed by expert physicians in a clinical environment.
Hair Mesotherapy Prices 2025
As of 2025, hair mesotherapy session fees in Türkiye vary from ₺1,200 to ₺2,500 depending on the clinic and cocktail content. Packaged 4–6 session programs usually offer a 15–25% discount advantage. With a free preliminary examination, you can learn the most suitable pricing according to your personal hair analysis, and plan your sessions with easy payment options and installment options.